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 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
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Genetics
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MeSH cloud (automatically populated)
About this section
The MeSH cloud below displays MeSH terms that are associated with this transcription factor. The physical size of the terms reflect the significance of their association with the transcription factor as determined by the Fisher's Exact Test. It should be noted that these associations do not necessarily imply a positive correlation between the described MeSH term and this transcription factor. For instance, if the MeSH term "apoptosis" occurs, it may indicate that this transcription factor can induce apoptosis (positive correlation), or prevent apoptosis (negative correlation). Methods: The transcription factor is mapped to a set of Pubmed publications through the gene-to-pubmed association as provided by NCBI. Then, a collection of MeSH terms associated with the papers are compiled, along with the frequency of each MeSH term. The Fisher's Exact Test is conducted on the frequency of each term in the collection, versus its average frequency, to determine its significance in the collection. More information on MeSH can be found on the MeSH homepage.
MeSH term Fisher's exact p-value
1 Hypercholesterolemia 5.0 x 10-5
2 Glomerulosclerosis, Focal Segmental 8.1 x 10-5
3 Zellweger Syndrome 0.0017
4 Hypobetalipoproteinemias 0.0026
5 Fatty Liver, Alcoholic 0.0032
6 Diabetes Mellitus, Experimental 0.0044
7 Charcot-Marie-Tooth Disease 0.0080
8 Lipodystrophy 0.011
9 Hyperhomocysteinemia 0.014
10 Gallstones 0.027
MeSH term Fisher's exact p-value
1 Lipid Metabolism Disorders 9.7 x 10-6
2 Fatty Liver 1.5 x 10-5
3 Dyslipidemias 4.5 x 10-5
4 Hypercholesterolemia 5.0 x 10-5
5 Metabolic Diseases 5.8 x 10-5
6 Nutritional and Metabolic Diseases 7.5 x 10-5
7 Glomerulosclerosis, Focal Segmental 8.1 x 10-5
8 Hyperlipidemias 0.00077
9 Zellweger Syndrome 0.0017
10 Hypobetalipoproteinemias 0.0026
11 Fatty Liver, Alcoholic 0.0032
12 Diabetes Mellitus, Experimental 0.0044
13 Cholelithiasis 0.0055
14 Hypolipoproteinemias 0.0066
15 Glomerulonephritis 0.0075
16 Charcot-Marie-Tooth Disease 0.0080
17 Peroxisomal Disorders 0.0098
18 Metabolism, Inborn Errors 0.010
19 Lipodystrophy 0.011
20 Hyperhomocysteinemia 0.014
21 Hereditary Sensory and Motor Neuropathy 0.014
22 Nephritis 0.018
23 Disease Models, Animal 0.024
24 Gallstones 0.027
25 Cholecystolithiasis 0.028
26 Liver Diseases, Alcoholic 0.037
27 Skin Diseases, Metabolic 0.042
28 Liver Diseases 0.042
29 Biliary Tract Diseases 0.049
MGI mammalian phenotype terms (automatically populated)