Recently visited
Please sign in to see a list of articles you recently visited.
Recently updated
 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
Comments (post)
There are no comments posted here... Yet.
Overview
There is no text here... Yet.
Structures
About this section
This section contains 3D PDB models of structural predictions for this transcription factor. METHODS: The template selection protocol follows that of Morozov and Siggia, in which templates are selected to optimize similarity of DNA-binding residues (Morozov AV, Siggia ED. PNAS 104(17):7068-73). This has been shown to increase modeling accuracy at the DNA-binding interface. For all solved structures containing DNA, amino acids within 4A of DNA (DNA-binding residues) are stored. Pfam domain hits of each DNA-bound chain are detected by hmmer, and each hit is added to a list mapping domain family name to chain hits. Pfam domain hits of each unsolved structure are detected by HMMER. For each identified Pfam family, the unsolved sequence is aligned to all solved family members (putative templates). Alignments are scored based on similarity of the DNA-binding residues in the template to the aligned residues of the unsolved sequence. For each subsequence of the unsolved protein identified as a DNA-binding domain, the top scoring template is selected. For sequences known to form homodimers, a homodimeric template is selected. The model is constructed from the template using Modeller 9v2. DNA bound to the template is added to the model by superimposition of the solved and modeled structures.
There are no structures here... Yet.
Family
Winged Helix-Turn-Helix » Forkhead Domain Family
 Foxa1
Mus musculus
 FOXA1
Homo sapiens
 FOXA2
Homo sapiens
 Foxa2
Mus musculus
 Foxa2
Rattus norvegicus
 Foxa3
Mus musculus
 FOXA3
Homo sapiens
FOXB1
Homo sapiens
Foxb1
Mus musculus
FOXC1
Homo sapiens
Foxc1
Mus musculus
FOXC2
Homo sapiens
Foxc2
Mus musculus
FOXD1
Homo sapiens
Foxd1
Mus musculus
FOXD2
Homo sapiens
Foxd2
Mus musculus
FOXD3
Homo sapiens
Foxd3
Mus musculus
FOXD4
Homo sapiens
Foxd4
Mus musculus
FOXE1
Homo sapiens
Foxe1
Mus musculus
FOXE3
Homo sapiens
Foxe3
Mus musculus
FOXF1
Homo sapiens
Foxf1a
Mus musculus
FOXF2
Homo sapiens
Foxf2
Mus musculus
FOXG1
Homo sapiens
Foxg1
Mus musculus
 Foxh1
Mus musculus
 FOXH1
Homo sapiens
FOXI1
Homo sapiens
Foxi1
Mus musculus
FOXJ1
Homo sapiens
Foxj1
Mus musculus
FOXJ2
Homo sapiens
Foxj2
Mus musculus
FOXJ3
Homo sapiens
Foxj3
Mus musculus
FOXK1
Homo sapiens
Foxk1
Mus musculus
FOXK2
Homo sapiens
Foxk2
Mus musculus
FOXL1
Homo sapiens
Foxl1
Mus musculus
 FOXL2
Homo sapiens
 Foxl2
Mus musculus
 FOXM1
Homo sapiens
 Foxm1
Mus musculus
FOXN1
Homo sapiens
Foxn1
Mus musculus
FOXN2
Homo sapiens
Foxn2
Mus musculus
FOXN3
Homo sapiens
Foxn3
Mus musculus
FOXN4
Homo sapiens
Foxn4
Mus musculus
 FOXO1
Homo sapiens
 Foxo1
Mus musculus
 FOXO3
Homo sapiens
 Foxo3
Mus musculus
 FOXO4
Homo sapiens
 Foxo4
Mus musculus
Foxo6
Mus musculus
 FOXP1
Homo sapiens
 Foxp1
Mus musculus
FOXP2
Homo sapiens
Foxp2
Mus musculus
FOXP3
Homo sapiens
Foxp3
Mus musculus
FOXP4
Homo sapiens
Foxp4
Mus musculus
FOXQ1
Homo sapiens
Foxq1
Mus musculus
FOXR1
Homo sapiens
Foxr1
Mus musculus
FOXR2
Homo sapiens
Foxr2
Mus musculus
 
Figures
There are no figures here... Yet.