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 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
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Gene Ontology (automatically populated)
molecular_function (GO:0003674)
binding (GO:0005488)
nucleic acid binding (GO:0003676)
 DNA binding (GO:0003677
 sequence-specific DNA binding (GO:0043565
transcription regulator activity (GO:0030528)
 transcription factor activity (GO:0003700
cellular_component (GO:0005575)
organelle (GO:0043226)
membrane-bounded organelle (GO:0043227)
intracellular membrane-bounded organelle (GO:0043231)
 nucleus (GO:0005634
biological_process (GO:0008150)
metabolic process (GO:0008152)
cellular metabolic process (GO:0044237)
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139)
 transcription (GO:0006350
biological regulation (GO:0065007)
regulation of biological process (GO:0050789)
regulation of cellular process (GO:0050794)
regulation of gene expression (GO:0010468)
 regulation of transcription (GO:0045449
 regulation of transcription, DNA-dependent (GO:0006355
 CategoryGO term IDTermEvidencePubmed
1BPGO:0045449regulation of transcriptionIEA(none)
2BPGO:0006355regulation of transcription, DNA-dependentIEA(none)
3BPGO:0006350transcriptionIEA(none)
4CCGO:0005634nucleusIEA(none)
5MFGO:0003677DNA bindingIEA(none)
6MFGO:0043565sequence-specific DNA bindingIEA(none)
7MFGO:0003700transcription factor activityIEA(none)
MeSH cloud (automatically populated)
About this section
The MeSH cloud below displays MeSH terms that are associated with this transcription factor. The physical size of the terms reflect the significance of their association with the transcription factor as determined by the Fisher's Exact Test. It should be noted that these associations do not necessarily imply a positive correlation between the described MeSH term and this transcription factor. For instance, if the MeSH term "apoptosis" occurs, it may indicate that this transcription factor can induce apoptosis (positive correlation), or prevent apoptosis (negative correlation). Methods: The transcription factor is mapped to a set of Pubmed publications through the gene-to-pubmed association as provided by NCBI. Then, a collection of MeSH terms associated with the papers are compiled, along with the frequency of each MeSH term. The Fisher's Exact Test is conducted on the frequency of each term in the collection, versus its average frequency, to determine its significance in the collection. More information on MeSH can be found on the MeSH homepage.
MeSH term Fisher's exact p-value
1 DNA, Complementary 3.3 x 10-21
2 Gene Library 1.3 x 10-13
3 Cloning, Molecular 4.4 x 10-11
4 Forkhead Transcription Factors 1.6 x 10-8
5 DNA Primers 8.3 x 10-7
6 Transcription Initiation Site 9.8 x 10-7
7 Gene Expression Regulation, Developmental 6.9 x 10-6
8 Genetic Vectors 1.9 x 10-5
9 Embryo, Mammalian 3.0 x 10-5
10 In Situ Hybridization 3.3 x 10-5
11 Databases, Genetic 9.9 x 10-5
12 Open Reading Frames 0.00013
13 Transcription, Genetic 0.00020
14 Green Fluorescent Proteins 0.00023
15 RNA, Antisense 0.00024
16 Genomics 0.00032
17 Protein-Lysine 6-Oxidase 0.00065
18 Gene Expression Profiling 0.00070
19 RNA, Complementary 0.0011
20 Image Cytometry 0.0012
21 RNA Splice Sites 0.0013
22 Terminator Regions, Genetic 0.0013
23 Ventral Tegmental Area 0.0016
24 RNA Caps 0.0017
25 Sequence Analysis, RNA 0.0019
26 Protein Structure, Tertiary 0.0024
27 Connexin 43 0.0024
28 Neocortex 0.0029
29 Plasmids 0.0030
30 Promoter Regions, Genetic 0.0031
31 Reverse Transcriptase Polymerase Chain Reaction 0.0032
32 3' Untranslated Regions 0.0039
33 Expressed Sequence Tags 0.0054
34 Integrases 0.0054
35 Bacteriophage lambda 0.0055
36 Mice, Inbred C57BL 0.0063
37 Schistosoma mansoni 0.0069
38 Zebrafish 0.0078
39 Proteome 0.0089
40 Cadherins 0.0091
41 Templates, Genetic 0.0093
42 Stem Cells 0.0094
43 Substantia Nigra 0.010
44 Electrophoresis, Capillary 0.011
45 Genome, Human 0.011
46 RNA Interference 0.011
47 Spermatogenesis 0.011
48 Reproducibility of Results 0.012
49 Alternative Splicing 0.012
50 National Institutes of Health (U.S.) 0.014
51 beta-Galactosidase 0.014
52 Xenopus laevis 0.017
53 Genes, Reporter 0.021
54 Amino Acid Motifs 0.023
55 Thalamus 0.027
56 Conserved Sequence 0.027
57 Internet 0.028
58 Sensitivity and Specificity 0.028
59 Multiple Sclerosis 0.030
60 DNA Mutational Analysis 0.031
61 Genetic Markers 0.033
62 Physical Chromosome Mapping 0.036
63 Clone Cells 0.036
64 Corpus Striatum 0.037
65 Brain Chemistry 0.040
MeSH term Fisher's exact p-value
1 Nucleic Acid Probes 7.5 x 10-26
2 Molecular Probes 1.0 x 10-25
3 Mice 7.2 x 10-23
4 DNA, Complementary 3.3 x 10-21
5 DNA, Single-Stranded 1.8 x 10-20
6 DNA Probes 1.7 x 10-19
7 Laboratory Chemicals 2.4 x 10-19
8 Genetic Structures 1.9 x 10-17
9 Murinae 6.0 x 10-17
10 Muridae 1.1 x 10-16
11 Rodentia 2.4 x 10-16
12 Nucleic Acids 4.6 x 10-16
13 Nucleic Acids, Nucleotides, and Nucleosides 1.0 x 10-15
14 Specialty Uses of Chemicals 3.2 x 10-15
15 Genetic Phenomena 1.3 x 10-14
16 Gene Library 1.3 x 10-13
17 DNA 1.6 x 10-13
18 Genetic Techniques 1.8 x 10-13
19 Computational Biology 3.7 x 10-12
20 Genome 2.8 x 10-11
21 Cloning, Molecular 4.4 x 10-11
22 RNA, Messenger 6.2 x 10-11
23 RNA 1.0 x 10-10
24 Chemical Actions and Uses 4.7 x 10-9
25 Gene Components 9.0 x 10-9
26 Forkhead Transcription Factors 1.6 x 10-8
27 Winged-Helix Transcription Factors 1.6 x 10-8
28 Biology 1.0 x 10-7
29 Base Sequence 1.0 x 10-7
30 Molecular Structure 1.7 x 10-7
31 DNA Primers 8.3 x 10-7
32 Biochemical Phenomena 9.5 x 10-7
33 Transcription Initiation Site 9.8 x 10-7
34 Regulatory Sequences, Ribonucleic Acid 1.3 x 10-6
35 Oligodeoxyribonucleotides 2.0 x 10-6
36 Sequence Analysis, DNA 2.1 x 10-6
37 Gene Expression Regulation 2.4 x 10-6
38 Polymerase Chain Reaction 3.2 x 10-6
39 Nucleic Acid Amplification Techniques 3.3 x 10-6
40 Biological Science Disciplines 3.4 x 10-6
41 Gene Expression 4.2 x 10-6
42 Genes 5.0 x 10-6
43 Oligonucleotides 5.7 x 10-6
44 Genetic Processes 6.5 x 10-6
45 Gene Expression Regulation, Developmental 6.9 x 10-6
46 RNA Probes 9.0 x 10-6
47 Chemical Phenomena 9.0 x 10-6
48 Genome Components 9.1 x 10-6
49 Databases, Factual 9.3 x 10-6
50 Polynucleotides 1.0 x 10-5
51 Information Science 1.0 x 10-5
52 Sequence Analysis 1.3 x 10-5
53 Molecular Sequence Data 1.6 x 10-5
54 Databases as Topic 1.9 x 10-5
55 Genetic Vectors 1.9 x 10-5
56 Documentation 2.2 x 10-5
57 Information Services 2.9 x 10-5
58 Information Storage and Retrieval 3.0 x 10-5
59 Embryo, Mammalian 3.0 x 10-5
60 Nucleotides 3.2 x 10-5
61 In Situ Hybridization 3.3 x 10-5
62 Regulatory Elements, Transcriptional 9.7 x 10-5
63 Databases, Genetic 9.9 x 10-5
64 Regulatory Sequences, Nucleic Acid 0.00013
65 Open Reading Frames 0.00013
66 Reading Frames 0.00014
67 Transcription Factors 0.00014
68 Information Systems 0.00015
69 Natural Science Disciplines 0.00017
70 Transcription, Genetic 0.00020
71 Green Fluorescent Proteins 0.00023
72 RNA Splicing 0.00024
73 RNA, Antisense 0.00024
74 Staining and Labeling 0.00025
75 Genomics 0.00032
76 Nucleic Acid Hybridization 0.00035
77 RNA Processing, Post-Transcriptional 0.00040
78 Antisense Elements (Genetics) 0.00060
79 RNA, Untranslated 0.00061
80 Histocytological Preparation Techniques 0.00063
81 Protein-Lysine 6-Oxidase 0.00065
82 Luminescent Proteins 0.00065
83 Gene Expression Profiling 0.00070
84 Genetic Code 0.00079
85 Mesencephalon 0.00093
86 Medical Informatics Applications 0.00093
87 Medical Informatics 0.00098
88 RNA, Complementary 0.0011
89 Image Cytometry 0.0012
90 RNA Splice Sites 0.0013
91 Terminator Regions, Genetic 0.0013
92 Histological Techniques 0.0014
93 Ventral Tegmental Area 0.0016
94 RNA Caps 0.0017
95 Sequence Analysis, RNA 0.0019
96 Protein Structure, Tertiary 0.0024
97 Connexin 43 0.0024
98 Clinical Laboratory Techniques 0.0027
99 Neocortex 0.0029
100 Embryonic Structures 0.0030
101 Plasmids 0.0030
102 Promoter Regions, Genetic 0.0031
103 Reverse Transcriptase Polymerase Chain Reaction 0.0032
104 DNA-Binding Proteins 0.0033
105 3' Untranslated Regions 0.0039
106 Chromosome Mapping 0.0047
107 Biochemical Processes 0.0047
108 Cytological Techniques 0.0047
109 Animal Population Groups 0.0048
110 Mammals 0.0052
111 Expressed Sequence Tags 0.0054
112 Integrases 0.0054
113 Bacteriophage lambda 0.0055
114 Siphoviridae 0.0056
115 Connexins 0.0056
116 Genetics 0.0056
117 Mice, Inbred C57BL 0.0063
118 Brain Stem 0.0069
119 Schistosoma mansoni 0.0069
120 Investigative Techniques 0.0069
121 Vertebrates 0.0072
122 Chordata 0.0072
123 Untranslated Regions 0.0076
124 Zebrafish 0.0078
125 Metabolic Phenomena 0.0084
126 Proteome 0.0089
127 Cadherins 0.0091
128 Caudovirales 0.0092
129 Templates, Genetic 0.0093
130 Stem Cells 0.0094
131 Recombinases 0.0097
132 Mathematical Concepts 0.010
133 Substantia Nigra 0.010
134 Electrophoresis, Capillary 0.011
135 Schistosoma 0.011
136 Schistosomatidae 0.011
137 Genome, Human 0.011
138 RNA Interference 0.011
139 Spermatogenesis 0.011
140 Animals 0.012
141 Reproducibility of Results 0.012
142 Chemical Processes 0.012
143 Alternative Splicing 0.012
144 National Institutes of Health (U.S.) 0.014
145 beta-Galactosidase 0.014
146 Gametogenesis 0.016
147 Proteins 0.016
148 Xenopus laevis 0.017
149 Tegmentum Mesencephali 0.017
150 Cyprinidae 0.018
151 Eukaryota 0.018
152 Cerebral Cortex 0.018
153 Protein Conformation 0.018
154 Cypriniformes 0.018
155 Galactosidases 0.019
156 Gene Silencing 0.020
157 Trematoda 0.020
158 Genes, Reporter 0.021
159 Metabolism 0.023
160 Amino Acid Motifs 0.023
161 Coliphages 0.025
162 Cerebrum 0.026
163 Thalamus 0.027
164 Conserved Sequence 0.027
165 Internet 0.028
166 Sensitivity and Specificity 0.028
167 Epigenesis, Genetic 0.029
168 Telencephalon 0.029
169 Xenopus 0.029
170 Pipidae 0.029
171 Platyhelminths 0.030
172 Multiple Sclerosis 0.030
173 DNA Mutational Analysis 0.031
174 Genetic Markers 0.033
175 Molecular Conformation 0.034
176 Reproduction 0.035
177 Mice, Inbred Strains 0.035
178 Physical Chromosome Mapping 0.036
179 DNA, Intergenic 0.036
180 Brain 0.036
181 Clone Cells 0.036
182 Reproductive Physiological Processes 0.037
183 Corpus Striatum 0.037
184 Computer Communication Networks 0.037
185 Amino Acids, Peptides, and Proteins 0.037
186 Demyelinating Autoimmune Diseases, CNS 0.039
187 Brain Chemistry 0.040
188 Guanine Nucleotides 0.040
189 Amino Acid Oxidoreductases 0.041
190 Bacteriophages 0.041
191 Central Nervous System 0.046
192 Amino Acid Sequence 0.048
193 Reproductive Physiological Phenomena 0.049
 3' Untranslated Regions   Alternative Splicing   Amino Acid Motifs   Bacteriophage lambda   beta-Galactosidase   Brain Chemistry   Cadherins   Clone Cells   Cloning, Molecular   Connexin 43   Conserved Sequence   Corpus Striatum   Databases, Genetic   DNA Mutational Analysis   DNA Primers   DNA, Complementary   Electrophoresis, Capillary   Embryo, Mammalian   Expressed Sequence Tags   Forkhead Transcription Factors   Gene Expression Profiling   Gene Expression Regulation, Developmental   Gene Library   Genes, Reporter   Genetic Markers   Genetic Vectors   Genome, Human   Genomics   Green Fluorescent Proteins   Image Cytometry   In Situ Hybridization   Integrases   Internet   Mice, Inbred C57BL   Multiple Sclerosis   National Institutes of Health (U.S.)   Neocortex   Open Reading Frames   Physical Chromosome Mapping   Plasmids   Promoter Regions, Genetic   Protein Structure, Tertiary   Protein-Lysine 6-Oxidase   Proteome   Reproducibility of Results   Reverse Transcriptase Polymerase Chain Reaction   RNA Caps   RNA Interference   RNA Splice Sites   RNA, Antisense   RNA, Complementary   Schistosoma mansoni   Sensitivity and Specificity   Sequence Analysis, RNA   Spermatogenesis   Stem Cells   Substantia Nigra   Templates, Genetic   Terminator Regions, Genetic   Thalamus   Transcription Initiation Site   Transcription, Genetic   Ventral Tegmental Area   Xenopus laevis   Zebrafish