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 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
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Gene Ontology (automatically populated)
molecular_function (GO:0003674)
binding (GO:0005488)
nucleic acid binding (GO:0003676)
DNA binding (GO:0003677)
 sequence-specific DNA binding (GO:0043565
 protein binding (GO:0005515
enzyme binding (GO:0019899)
kinase binding (GO:0019900)
 protein kinase binding (GO:0019901
transcription regulator activity (GO:0030528)
 transcription factor activity (GO:0003700
 transcription activator activity (GO:0016563
cellular_component (GO:0005575)
organelle (GO:0043226)
membrane-bounded organelle (GO:0043227)
intracellular membrane-bounded organelle (GO:0043231)
 nucleus (GO:0005634
cell part (GO:0044464)
cell fraction (GO:0000267)
 membrane fraction (GO:0005624
intracellular part (GO:0044424)
 cytoplasm (GO:0005737
cytoplasmic part (GO:0044444)
 cytosol (GO:0005829
biological_process (GO:0008150)
cellular process (GO:0009987)
cell maturation (GO:0048469)
 oocyte maturation (GO:0001556
cellular developmental process (GO:0048869)
cell death (GO:0008219)
programmed cell death (GO:0012501)
 apoptosis (GO:0006915
reproductive process (GO:0022414)
reproductive process in a multicellular organism (GO:0048609)
ovulation (GO:0030728)
 ovulation from ovarian follicle (GO:0001542
developmental process (GO:0032502)
developmental growth (GO:0048589)
 antral ovarian follicle growth (GO:0001547
rhythmic process (GO:0048511)
ovulation cycle process (GO:0022602)
 initiation of primordial ovarian follicle growth (GO:0001544
response to stimulus (GO:0050896)
response to endogenous stimulus (GO:0009719)
 response to DNA damage stimulus (GO:0006974
biological regulation (GO:0065007)
regulation of biological process (GO:0050789)
positive regulation of biological process (GO:0048518)
positive regulation of cellular process (GO:0048522)
positive regulation of programmed cell death (GO:0043068)
induction of programmed cell death (GO:0012502)
 induction of apoptosis (GO:0006917
positive regulation of cell differentiation (GO:0045597)
positive regulation of myeloid cell differentiation (GO:0045639)
 positive regulation of erythrocyte differentiation (GO:0045648
regulation of cellular process (GO:0050794)
regulation of gene expression (GO:0010468)
regulation of transcription (GO:0045449)
 regulation of transcription, DNA-dependent (GO:0006355
regulation of gene-specific transcription (GO:0032583)
regulation of gene-specific transcription from RNA polymerase II promoter (GO:0010551)
 negative regulation of gene-specific transcription from RNA polymerase II promoter (GO:0010553
positive regulation of transcription, DNA-dependent (GO:0045893)
 positive regulation of transcription from RNA polymerase II promoter (GO:0045944
regulation of biological quality (GO:0065008)
homeostatic process (GO:0042592)
chemical homeostasis (GO:0048878)
carbohydrate homeostasis (GO:0033500)
 glucose homeostasis (GO:0042593
 CategoryGO term IDTermEvidencePubmed
1BPGO:0001547antral ovarian follicle growthIEA(none)
2BPGO:0006915apoptosisIDA10102273
3BPGO:0042593glucose homeostasisIEA(none)
4BPGO:0006917induction of apoptosisIEA(none)
5BPGO:0001544initiation of primordial ovarian follicle growthIEA(none)
6BPGO:0010553negative regulation of gene-specific transcription from RNA polymerase II promoterIMP18787191
7BPGO:0001556oocyte maturationIEA(none)
8BPGO:0001542ovulation from ovarian follicleIEA(none)
9BPGO:0045648positive regulation of erythrocyte differentiationIDA14734530
10BPGO:0045944positive regulation of transcription from RNA polymerase II promoterIDA14734530
11BPGO:0006355regulation of transcription, DNA-dependentIEA(none)
12BPGO:0006974response to DNA damage stimulusIEA(none)
13CCGO:0005737cytoplasmIDA10102273
14CCGO:0005829cytosolIEA(none)
15CCGO:0005624membrane fractionIEA(none)
16CCGO:0005634nucleusIDA16751106
17MFGO:0005515protein bindingIPI16809346
18MFGO:0019901protein kinase bindingIPI18593906
19MFGO:0043565sequence-specific DNA bindingIDA10102273
20MFGO:0016563transcription activator activityIDA10102273
21MFGO:0003700transcription factor activityIDA14734530
MeSH cloud (automatically populated)
About this section
The MeSH cloud below displays MeSH terms that are associated with this transcription factor. The physical size of the terms reflect the significance of their association with the transcription factor as determined by the Fisher's Exact Test. It should be noted that these associations do not necessarily imply a positive correlation between the described MeSH term and this transcription factor. For instance, if the MeSH term "apoptosis" occurs, it may indicate that this transcription factor can induce apoptosis (positive correlation), or prevent apoptosis (negative correlation). Methods: The transcription factor is mapped to a set of Pubmed publications through the gene-to-pubmed association as provided by NCBI. Then, a collection of MeSH terms associated with the papers are compiled, along with the frequency of each MeSH term. The Fisher's Exact Test is conducted on the frequency of each term in the collection, versus its average frequency, to determine its significance in the collection. More information on MeSH can be found on the MeSH homepage.
MeSH term Fisher's exact p-value
1 Forkhead Transcription Factors 0
2 Proto-Oncogene Proteins c-akt 1.8 x 10-69
3 RNA, Small Interfering 4.5 x 10-45
4 Phosphorylation 6.8 x 10-45
5 1-Phosphatidylinositol 3-Kinase 3.7 x 10-43
6 Signal Transduction 7.3 x 10-37
7 Cyclin-Dependent Kinase Inhibitor p27 1.0 x 10-31
8 Gene Expression Regulation, Neoplastic 4.2 x 10-30
9 Transcriptional Activation 8.8 x 10-29
10 Humans 2.1 x 10-27
11 Oxidative Stress 1.2 x 10-22
12 Transcription, Genetic 2.0 x 10-22
13 Transfection 2.8 x 10-19
14 Active Transport, Cell Nucleus 3.3 x 10-19
15 Cell Survival 4.8 x 10-19
16 Protein Binding 7.8 x 10-19
17 14-3-3 Proteins 9.8 x 10-18
18 Down-Regulation 1.5 x 10-13
19 Endothelial Cells 3.9 x 10-13
20 Up-Regulation 7.8 x 10-13
21 DNA, Complementary 1.2 x 10-12
22 RNA, Messenger 2.2 x 10-12
23 Reverse Transcriptase Polymerase Chain Reaction 4.2 x 10-12
24 vpr Gene Products, Human Immunodeficiency Virus 5.5 x 10-12
25 Chromatin Immunoprecipitation 2.4 x 10-11
26 Blotting, Western 1.4 x 10-10
27 Polymorphism, Single Nucleotide 1.0 x 10-9
28 TNF-Related Apoptosis-Inducing Ligand 4.8 x 10-9
29 Sirtuin 1 8.3 x 10-9
30 Immediate-Early Proteins 9.6 x 10-9
31 Glycogen Synthase Kinase 3 1.2 x 10-8
32 Longevity 2.0 x 10-8
33 Genes, Reporter 2.4 x 10-8
34 Shc Signaling Adaptor Proteins 3.7 x 10-8
35 Prostatic Neoplasms 3.7 x 10-8
36 CASP8 and FADD-Like Apoptosis Regulating Protein 4.4 x 10-8
37 Luciferases 7.1 x 10-8
38 Superoxide Dismutase 7.3 x 10-8
39 Ovarian Failure, Premature 7.4 x 10-8
40 Estrogen Receptor alpha 8.5 x 10-8
41 Hydrogen Peroxide 1.3 x 10-7
42 DNA Primers 1.4 x 10-7
43 Neuroblastoma 5.0 x 10-7
44 STAT5 Transcription Factor 5.2 x 10-7
45 Recombinant Fusion Proteins 6.6 x 10-7
46 I-kappa B Kinase 8.0 x 10-7
47 Microarray Analysis 8.6 x 10-7
48 Umbilical Veins 1.2 x 10-6
49 PTEN Phosphohydrolase 1.2 x 10-6
50 Acetylation 1.4 x 10-6
51 Chromosomes, Human, Pair 6 2.7 x 10-6
52 Cell Transformation, Neoplastic 3.0 x 10-6
53 Anoikis 3.4 x 10-6
54 Enzyme Activation 4.1 x 10-6
55 Plasmids 4.1 x 10-6
56 Open Reading Frames 1.0 x 10-5
57 Fas-Associated Death Domain Protein 1.2 x 10-5
58 Gene Expression Profiling 1.5 x 10-5
59 beta Catenin 1.5 x 10-5
60 COS Cells 1.6 x 10-5
61 Amino Acid Sequence 2.2 x 10-5
62 Mammary Glands, Human 2.3 x 10-5
63 HCT116 Cells 2.7 x 10-5
64 Two-Hybrid System Techniques 2.7 x 10-5
65 HIV-1 3.4 x 10-5
66 Peroxiredoxins 3.6 x 10-5
67 Receptors, Glucocorticoid 3.7 x 10-5
68 Jurkat Cells 3.8 x 10-5
69 Receptors, Androgen 4.0 x 10-5
70 Antigens, CD95 4.4 x 10-5
71 Caenorhabditis elegans 5.7 x 10-5
72 Repressor Proteins 5.9 x 10-5
73 Mice, Knockout 6.8 x 10-5
74 Protein Kinase Inhibitors 7.1 x 10-5
75 AMP-Activated Protein Kinases 7.6 x 10-5
76 Tyrosine 3-Monooxygenase 0.00010
77 Caspase 3 0.00012
78 Cytoprotection 0.00017
79 HT29 Cells 0.00018
80 Proto-Oncogene Proteins c-mdm2 0.00018
81 Caspase 8 0.00021
82 Sirtuin 3 0.00021
83 Caspase 9 0.00025
84 Fusion Proteins, bcr-abl 0.00030
85 Piperazines 0.00036
86 K562 Cells 0.00053
87 Genetic Predisposition to Disease 0.00054
88 Guanine Nucleotide Exchange Factors 0.00059
89 NIH 3T3 Cells 0.00064
90 Cercopithecus aethiops 0.00064
91 Insulin-Like Growth Factor I 0.00066
92 Hela Cells 0.00067
93 Response Elements 0.00067
94 Citrobacter rodentium 0.00081
95 Caenorhabditis elegans Proteins 0.00082
96 Culture Media, Serum-Free 0.00086
97 Adenoviridae 0.00094
98 Proto-Oncogene Proteins c-myc 0.00094
99 Androstadienes 0.0010
100 Gene Library 0.0010
101 Tumor Suppressor Protein p53 0.0011
102 Cysteine-Rich Protein 61 0.0014
103 Tunica Intima 0.0014
104 Collagen Type XI 0.0015
105 Papilloma, Intraductal 0.0016
106 Transforming Growth Factor beta 0.0016
107 Core Binding Factor Alpha 3 Subunit 0.0016
108 Glypicans 0.0017
109 Threonine 0.0017
110 Tumor Necrosis Factor-alpha 0.0017
111 Linkage Disequilibrium 0.0018
112 Proto-Oncogene Proteins c-pim-1 0.0019
113 Pigment Epithelium of Eye 0.0021
114 Atherosclerosis 0.0021
115 Oxidants 0.0022
116 Immunologic Memory 0.0022
117 Luteinization 0.0025
118 Hydroxymethylglutaryl-CoA Synthase 0.0026
119 Cell Aging 0.0026
120 Protein-Arginine N-Methyltransferases 0.0029
121 Rhabdomyosarcoma, Alveolar 0.0029
122 Cyclin D2 0.0032
123 Acetyl-CoA C-Acetyltransferase 0.0033
124 Interleukin-8 0.0033
125 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 0.0034
126 Transduction, Genetic 0.0035
127 Etoposide 0.0035
128 Ribosomal Protein S6 Kinases, 90-kDa 0.0036
129 Genome, Human 0.0037
130 Muscle, Smooth, Vascular 0.0038
131 RNA Interference 0.0038
132 Microphthalmia-Associated Transcription Factor 0.0040
133 Mutagenesis, Site-Directed 0.0041
134 Myostatin 0.0041
135 Proto-Oncogene Proteins c-rel 0.0042
136 Hepatocytes 0.0042
137 Proteomics 0.0044
138 Tamoxifen 0.0050
139 Retinoblastoma-Like Protein p130 0.0050
140 Radiation Hybrid Mapping 0.0052
141 Oncogene Protein v-akt 0.0055
142 HIV-Associated Lipodystrophy Syndrome 0.0055
143 Drug Resistance, Neoplasm 0.0057
144 Extracellular Signal-Regulated MAP Kinases 0.0059
145 Pyruvaldehyde 0.0060
146 National Institutes of Health (U.S.) 0.0060
147 Tretinoin 0.0062
148 fms-Like Tyrosine Kinase 3 0.0062
149 Aminoimidazole Carboxamide 0.0063
150 Receptors, TNF-Related Apoptosis-Inducing Ligand 0.0064
151 NF-kappa B p50 Subunit 0.0066
152 Myeloid-Lymphoid Leukemia Protein 0.0068
153 Genes, Dominant 0.0068
154 Adenomatous Polyposis Coli Protein 0.0069
155 Erythropoietin 0.0071
156 Receptor, Fibroblast Growth Factor, Type 1 0.0071
157 Mitochondria 0.0071
158 Gene Knockdown Techniques 0.0072
159 SKP Cullin F-Box Protein Ligases 0.0073
160 Insulin Antagonists 0.0074
161 cdc25 Phosphatases 0.0074
162 Matrix Metalloproteinase 13 0.0075
163 Slovenia 0.0076
164 Complement Factor H 0.0077
165 Penetrance 0.0078
166 Genome-Wide Association Study 0.0079
167 nef Gene Products, Human Immunodeficiency Virus 0.0079
168 Ecdysterone 0.0081
169 Fibroadenoma 0.0084
170 Spheroids, Cellular 0.0087
171 Androgens 0.0088
172 Protein Tyrosine Phosphatase, Non-Receptor Type 1 0.0088
173 Ubiquitination 0.0090
174 5' Flanking Region 0.0092
175 Microtubule-Associated Proteins 0.0092
176 G0 Phase 0.0094
177 Core Binding Factor Alpha 2 Subunit 0.0096
178 Ecdysone 0.0097
179 Ubiquitin Thiolesterase 0.010
180 Chromosomes, Human, Pair 20 0.010
181 Artificial Gene Fusion 0.010
182 Receptors, Tumor Necrosis Factor, Type II 0.010
183 Translocation, Genetic 0.010
184 Sequence Alignment 0.011
185 Cyclin E 0.011
186 Amino Acid Substitution 0.012
187 Aorta, Thoracic 0.012
188 Haplotypes 0.012
189 Hyperplasia 0.014
190 Mice, Inbred C57BL 0.014
191 Glutathione Disulfide 0.014
192 Dendritic Cells 0.014
193 Dermis 0.014
194 Milk Proteins 0.014
195 tat Gene Products, Human Immunodeficiency Virus 0.015
196 rho-Associated Kinases 0.015
197 Insulin 0.015
198 Phosphoserine 0.016
199 Chemokine CXCL12 0.016
200 Gene Deletion 0.016
201 Flow Cytometry 0.017
202 Matrix Metalloproteinase 3 0.017
203 Lithium Chloride 0.017
204 Receptors, Tumor Necrosis Factor, Type I 0.017
205 Disease Progression 0.017
206 Pseudogenes 0.018
207 Enzyme Induction 0.019
208 Trabecular Meshwork 0.019
209 Peptide Fragments 0.019
210 Biotinylation 0.020
211 Neutrophil Activation 0.020
212 Timolol 0.020
213 Estrogen Receptor beta 0.020
214 Annexin A5 0.020
215 Feedback, Physiological 0.020
216 Insulin-Like Growth Factor Binding Protein 3 0.021
217 Comet Assay 0.021
218 Tissue Inhibitor of Metalloproteinase-1 0.021
219 Chromosomes, Human, Pair 13 0.021
220 Thioredoxins 0.021
221 Exons 0.022
222 Insulin Resistance 0.022
223 Mice, Nude 0.022
224 Stem Cell Factor 0.023
225 Glycosylation End Products, Advanced 0.023
226 Receptor, IGF Type 1 0.023
227 Carotid Artery Injuries 0.024
228 DNA Repair 0.025
229 Cytosol 0.026
230 Paraffin Embedding 0.026
231 Mucin-1 0.026
232 G2 Phase 0.026
233 bcl-X Protein 0.026
234 omega-N-Methylarginine 0.027
235 Myosin Heavy Chains 0.027
236 Palmitic Acid 0.027
237 Genetic Markers 0.028
238 Thapsigargin 0.028
239 Smad Proteins 0.029
240 Chromosomes, Human, Pair 8 0.029
241 Vitamin B Complex 0.029
242 Dexamethasone 0.030
243 Neoplasm Invasiveness 0.031
244 Viral Matrix Proteins 0.031
245 Neoplasms, Hormone-Dependent 0.031
246 Neoplasm, Residual 0.032
247 Myocytes, Smooth Muscle 0.032
248 MicroRNAs 0.033
249 Gene Expression Regulation, Developmental 0.033
250 Staurosporine 0.035
251 Carotid Arteries 0.036
252 Gene Frequency 0.036
253 Lod Score 0.037
254 Fas Ligand Protein 0.038
255 Mesangial Cells 0.038
256 Neoadjuvant Therapy 0.038
257 Blotting, Northern 0.039
258 Hand Strength 0.039
259 Interleukin-3 0.040
260 Electrophoretic Mobility Shift Assay 0.040
261 Cysteine Proteinase Inhibitors 0.040
262 Expressed Sequence Tags 0.041
263 Brain-Derived Neurotrophic Factor 0.041
264 Models, Genetic 0.041
265 Granulosa Cells 0.042
266 Colon 0.042
267 Wnt Proteins 0.042
268 N-Formylmethionine Leucyl-Phenylalanine 0.043
269 G1 Phase 0.043
270 Estrogens 0.043
271 Hematologic Neoplasms 0.043
272 Transcription Factor AP-1 0.043
273 Amyloid beta-Protein Precursor 0.043
274 Chromosomes, Human, Pair 11 0.044
275 Anticarcinogenic Agents 0.045
276 Niacinamide 0.045
277 Microscopy, Fluorescence 0.045
278 Microglia 0.046
279 Protein Synthesis Inhibitors 0.046
280 Nitric Oxide Synthase Type III 0.047
281 Pakistan 0.048
282 Mass Spectrometry 0.049
283 Cyclin-Dependent Kinase Inhibitor p21 0.049
MeSH term Fisher's exact p-value
1 Forkhead Transcription Factors 0
2 Winged-Helix Transcription Factors 0
3 Transcription Factors 1.1 x 10-199
4 DNA-Binding Proteins 1.5 x 10-191
5 Genetic Phenomena 7.4 x 10-83
6 Intracellular Signaling Peptides and Proteins 7.5 x 10-83
7 Cells, Cultured 1.1 x 10-79
8 Gene Expression Regulation 3.7 x 10-75
9 Proteins 5.3 x 10-75
10 Neoplasm Proteins 2.8 x 10-74
11 Cell Physiological Processes 6.6 x 10-74
12 Phosphotransferases (Alcohol Group Acceptor) 6.9 x 10-70
13 Genetic Processes 9.6 x 10-70
14 Proto-Oncogene Proteins c-akt 1.8 x 10-69
15 Biochemical Processes 1.9 x 10-69
16 Amino Acids, Peptides, and Proteins 1.7 x 10-67
17 Cell Physiological Phenomena 4.0 x 10-66
18 Protein-Serine-Threonine Kinases 9.9 x 10-64
19 Cells 1.2 x 10-63
20 Protein Kinases 7.3 x 10-63
21 Cell Line 2.8 x 10-62
22 Phosphotransferases 2.2 x 10-61
23 Transferases 3.5 x 10-61
24 Chemical Processes 6.1 x 10-61
25 Apoptosis 8.3 x 10-60
26 Tumor Cells, Cultured 9.0 x 10-59
27 Cell Death 1.6 x 10-57
28 Oncogene Proteins 3.2 x 10-57
29 Proto-Oncogene Proteins 8.1 x 10-57
30 Biochemical Phenomena 2.7 x 10-56
31 Cell Line, Tumor 2.7 x 10-56
32 Metabolism 5.1 x 10-48
33 Chemical Phenomena 1.5 x 10-47
34 Enzymes 5.2 x 10-46
35 RNA, Small Interfering 4.5 x 10-45
36 Phosphorylation 6.8 x 10-45
37 Enzymes and Coenzymes 7.1 x 10-45
38 RNA, Antisense 1.5 x 10-43
39 1-Phosphatidylinositol 3-Kinase 3.7 x 10-43
40 Metabolic Phenomena 4.8 x 10-43
41 Antisense Elements (Genetics) 5.8 x 10-41
42 Organic Chemistry Processes 1.4 x 10-40
43 RNA, Untranslated 8.6 x 10-39
44 Peptides 8.9 x 10-38
45 Signal Transduction 7.3 x 10-37
46 Organic Chemistry Phenomena 2.8 x 10-36
47 Tumor Suppressor Proteins 2.7 x 10-32
48 Gene Components 4.3 x 10-32
49 Genetic Techniques 8.3 x 10-32
50 Cyclin-Dependent Kinase Inhibitor p27 1.0 x 10-31
51 Nucleic Acids 1.4 x 10-31
52 Gene Expression Regulation, Neoplastic 4.2 x 10-30
53 RNA 6.2 x 10-29
54 Transcriptional Activation 8.8 x 10-29
55 Adaptor Proteins, Signal Transducing 1.8 x 10-27
56 Humans 2.1 x 10-27
57 Hominidae 2.2 x 10-27
58 Nucleic Acids, Nucleotides, and Nucleosides 3.9 x 10-27
59 Catarrhini 4.4 x 10-27
60 Apoptosis Regulatory Proteins 5.6 x 10-27
61 Haplorhini 5.8 x 10-27
62 Primates 6.0 x 10-27
63 Genetic Structures 1.1 x 10-26
64 Genome 5.0 x 10-26
65 Cyclin-Dependent Kinase Inhibitor Proteins 5.2 x 10-26
66 Genes 3.4 x 10-25
67 Genome Components 9.5 x 10-25
68 Regulatory Elements, Transcriptional 1.1 x 10-24
69 Gene Expression 7.1 x 10-24
70 Promoter Regions, Genetic 8.0 x 10-24
71 Regulatory Sequences, Nucleic Acid 8.5 x 10-24
72 Viral Regulatory and Accessory Proteins 1.2 x 10-23
73 Physiological Processes 1.7 x 10-23
74 Cell Cycle Proteins 1.9 x 10-23
75 Oxidative Stress 1.2 x 10-22
76 Protein Transport 1.6 x 10-22
77 Transcription, Genetic 2.0 x 10-22
78 Molecular Structure 2.8 x 10-22
79 Gene Transfer Techniques 8.7 x 10-22
80 Base Sequence 4.2 x 10-20
81 Transfection 2.8 x 10-19
82 Active Transport, Cell Nucleus 3.3 x 10-19
83 Cell Survival 4.8 x 10-19
84 Protein Binding 7.8 x 10-19
85 Mammals 2.6 x 10-18
86 Stress, Physiological 3.1 x 10-18
87 Recombination, Genetic 6.3 x 10-18
88 14-3-3 Proteins 9.8 x 10-18
89 Cell Cycle 2.0 x 10-17
90 Viral Proteins 2.5 x 10-17
91 Physiological Phenomena 3.1 x 10-17
92 Vertebrates 3.2 x 10-17
93 Chordata 3.3 x 10-17
94 Cell Nucleus 3.4 x 10-17
95 Trans-Activators 3.4 x 10-16
96 Cell Proliferation 1.4 x 10-15
97 Animals 1.6 x 10-15
98 Cell Growth Processes 1.7 x 10-15
99 Epithelial Cells 1.9 x 10-15
100 DNA Probes 2.0 x 10-15
101 Nuclear Proteins 2.0 x 10-15
102 Nucleic Acid Probes 2.3 x 10-15
103 Carrier Proteins 2.9 x 10-15
104 Molecular Probes 3.3 x 10-15
105 Pharmacological Processes 9.9 x 10-15
106 Eukaryota 4.2 x 10-14
107 Mice 5.4 x 10-14
108 Organelles 6.1 x 10-14
109 Cytoplasmic Structures 9.5 x 10-14
110 Cytoplasm 1.2 x 10-13
111 Proline-Directed Protein Kinases 1.2 x 10-13
112 Down-Regulation 1.5 x 10-13
113 Endothelial Cells 3.9 x 10-13
114 Molecular Probe Techniques 4.1 x 10-13
115 Intracellular Space 4.2 x 10-13
116 Intercellular Signaling Peptides and Proteins 6.1 x 10-13
117 Up-Regulation 7.8 x 10-13
118 Protein Structure, Tertiary 8.4 x 10-13
119 Binding Sites 1.0 x 10-12
120 Reactive Oxygen Species 1.0 x 10-12
121 DNA, Complementary 1.2 x 10-12
122 Cellular Structures 1.5 x 10-12
123 RNA, Messenger 2.2 x 10-12
124 Reverse Transcriptase Polymerase Chain Reaction 4.2 x 10-12
125 Biological Transport, Active 4.6 x 10-12
126 vpr Gene Products, Human Immunodeficiency Virus 5.5 x 10-12
127 DNA, Single-Stranded 8.0 x 10-12
128 Receptors, Steroid 9.8 x 10-12
129 Neoplasms 1.1 x 10-11
130 Gene Products, vpr 1.1 x 10-11
131 Genetic Variation 1.2 x 10-11
132 Immunoblotting 1.3 x 10-11
133 Chromatin Immunoprecipitation 2.4 x 10-11
134 Receptors, Cytoplasmic and Nuclear 5.5 x 10-11
135 Oxidoreductases 9.1 x 10-11
136 Blotting, Western 1.4 x 10-10
137 Growth and Development 1.7 x 10-10
138 Group III Histone Deacetylases 1.8 x 10-10
139 Sirtuins 1.8 x 10-10
140 Molecular Sequence Data 2.1 x 10-10
141 Biological Transport 2.6 x 10-10
142 Free Radicals 2.7 x 10-10
143 Gene Silencing 3.4 x 10-10
144 Laboratory Chemicals 3.5 x 10-10
145 Documentation 5.8 x 10-10
146 Polymerase Chain Reaction 8.7 x 10-10
147 Nucleic Acid Amplification Techniques 1.0 x 10-9
148 Polymorphism, Single Nucleotide 1.0 x 10-9
149 Morpholines 1.1 x 10-9
150 Growth 1.2 x 10-9
151 Death Domain Receptor Signaling Adaptor Proteins 1.4 x 10-9
152 Information Services 1.6 x 10-9
153 Sequence Analysis 2.7 x 10-9
154 Pharmacological Phenomena 3.2 x 10-9
155 Epigenesis, Genetic 4.4 x 10-9
156 TNF-Related Apoptosis-Inducing Ligand 4.8 x 10-9
157 Cytokines 5.2 x 10-9
158 Immunoprecipitation 5.9 x 10-9
159 Sirtuin 1 8.3 x 10-9
160 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 9.4 x 10-9
161 Immediate-Early Proteins 9.6 x 10-9
162 Glycogen Synthase Kinase 3 1.2 x 10-8
163 Oligonucleotide Array Sequence Analysis 1.2 x 10-8
164 Serine 1.3 x 10-8
165 Glycogen Synthase Kinases 1.5 x 10-8
166 Biological Factors 1.5 x 10-8
167 Muridae 1.5 x 10-8
168 Rodentia 1.7 x 10-8
169 Murinae 1.9 x 10-8
170 Longevity 2.0 x 10-8
171 Oxazines 2.1 x 10-8
172 Genes, Reporter 2.4 x 10-8
173 Breast Neoplasms 3.7 x 10-8
174 Shc Signaling Adaptor Proteins 3.7 x 10-8
175 Prostatic Neoplasms 3.7 x 10-8
176 Caspases 4.4 x 10-8
177 CASP8 and FADD-Like Apoptosis Regulating Protein 4.4 x 10-8
178 Oligonucleotides 4.4 x 10-8
179 Histone Deacetylases 5.7 x 10-8
180 Luciferases 7.1 x 10-8
181 Superoxide Dismutase 7.3 x 10-8
182 Ovarian Failure, Premature 7.4 x 10-8
183 Breast Diseases 7.8 x 10-8
184 Cysteine Endopeptidases 8.4 x 10-8
185 Estrogen Receptor alpha 8.5 x 10-8
186 Cysteine Proteases 8.7 x 10-8
187 Protein Conformation 1.0 x 10-7
188 Conserved Sequence 1.0 x 10-7
189 Hydrogen Peroxide 1.3 x 10-7
190 Models, Biological 1.4 x 10-7
191 DNA Primers 1.4 x 10-7
192 Specialty Uses of Chemicals 1.6 x 10-7
193 Polynucleotides 1.6 x 10-7
194 Prostatic Diseases 1.8 x 10-7
195 Tumor Necrosis Factors 2.1 x 10-7
196 Mutation 2.4 x 10-7
197 Stem Cells 2.8 x 10-7
198 Cell Line, Transformed 2.9 x 10-7
199 Genital Neoplasms, Male 3.8 x 10-7
200 DNA 4.1 x 10-7
201 Mitogen-Activated Protein Kinases 4.2 x 10-7
202 Neoplastic Processes 4.6 x 10-7
203 Fibroblasts 4.9 x 10-7
204 Neuroblastoma 5.0 x 10-7
205 Polymorphism, Genetic 5.0 x 10-7
206 STAT5 Transcription Factor 5.2 x 10-7
207 Investigative Techniques 5.3 x 10-7
208 Chemical Actions and Uses 5.5 x 10-7
209 Luminescent Proteins 5.8 x 10-7
210 Peroxides 6.0 x 10-7
211 Recombinant Fusion Proteins 6.6 x 10-7
212 Neuroectodermal Tumors, Primitive, Peripheral 6.7 x 10-7
213 Hydrolases 7.7 x 10-7
214 Oligodeoxyribonucleotides 7.8 x 10-7
215 I-kappa B Kinase 8.0 x 10-7
216 Microarray Analysis 8.6 x 10-7
217 Oxygen Compounds 1.1 x 10-6
218 Immunoassay 1.2 x 10-6
219 Umbilical Veins 1.2 x 10-6
220 PTEN Phosphohydrolase 1.2 x 10-6
221 Microchip Analytical Procedures 1.3 x 10-6
222 Acetylation 1.4 x 10-6
223 Endopeptidases 1.5 x 10-6
224 Cloning, Molecular 1.5 x 10-6
225 Neoplasms by Site 1.7 x 10-6
226 Protein Processing, Post-Translational 1.7 x 10-6
227 Protein Modification, Translational 1.8 x 10-6
228 Neuroectodermal Tumors, Primitive 1.8 x 10-6
229 Animals, Genetically Modified 1.9 x 10-6
230 Enzyme Inhibitors 2.4 x 10-6
231 Receptors, Death Domain 2.4 x 10-6
232 Chromones 2.5 x 10-6
233 Receptors, Tumor Necrosis Factor 2.5 x 10-6
234 Chromosomes, Human, Pair 6 2.7 x 10-6
235 Cell Transformation, Neoplastic 3.0 x 10-6
236 Molecular Conformation 3.2 x 10-6
237 Anoikis 3.4 x 10-6
238 Biological Markers 3.4 x 10-6
239 Protein Biosynthesis 3.6 x 10-6
240 Enzyme Activation 4.1 x 10-6
241 Plasmids 4.1 x 10-6
242 Peptide Biosynthesis 4.7 x 10-6
243 Organisms, Genetically Modified 4.9 x 10-6
244 Recombinant Proteins 7.5 x 10-6
245 Peptide Hydrolases 8.0 x 10-6
246 Acylation 8.4 x 10-6
247 Connective Tissue Cells 9.2 x 10-6
248 Open Reading Frames 1.0 x 10-5
249 Mice, Transgenic 1.0 x 10-5
250 Reading Frames 1.1 x 10-5
251 Fas-Associated Death Domain Protein 1.2 x 10-5
252 Protein-Tyrosine Kinases 1.2 x 10-5
253 Genotype 1.2 x 10-5
254 Immunologic Techniques 1.2 x 10-5
255 Human Immunodeficiency Virus Proteins 1.4 x 10-5
256 Gene Expression Profiling 1.5 x 10-5
257 beta Catenin 1.5 x 10-5
258 COS Cells 1.6 x 10-5
259 Umbilical Cord 1.6 x 10-5
260 Neoplasms, Neuroepithelial 1.8 x 10-5
261 Armadillo Domain Proteins 1.9 x 10-5
262 Catenins 1.9 x 10-5
263 Amino Acid Sequence 2.2 x 10-5
264 Mammary Glands, Human 2.3 x 10-5
265 Proto-Oncogene Proteins c-bcl-2 2.3 x 10-5
266 Phenotype 2.5 x 10-5
267 Computational Biology 2.7 x 10-5
268 Chemotactic Factors 2.7 x 10-5
269 HCT116 Cells 2.7 x 10-5
270 Two-Hybrid System Techniques 2.7 x 10-5
271 Amino Acids, Neutral 2.9 x 10-5
272 HIV-1 3.4 x 10-5
273 Peroxiredoxins 3.6 x 10-5
274 Mice, Mutant Strains 3.6 x 10-5
275 Receptors, Glucocorticoid 3.7 x 10-5
276 Cell Differentiation 3.8 x 10-5
277 Jurkat Cells 3.8 x 10-5
278 3T3 Cells 3.9 x 10-5
279 Receptors, Androgen 4.0 x 10-5
280 Antigens, CD95 4.4 x 10-5
281 ADP Ribose Transferases 4.5 x 10-5
282 Erythroid Precursor Cells 4.8 x 10-5
283 STAT Transcription Factors 5.0 x 10-5
284 Caenorhabditis elegans 5.7 x 10-5
285 Repressor Proteins 5.9 x 10-5
286 Receptors, Estrogen 6.3 x 10-5
287 Ubiquitin-Protein Ligases 6.5 x 10-5
288 Membrane Proteins 6.7 x 10-5
289 Mice, Knockout 6.8 x 10-5
290 Protein Kinase Inhibitors 7.1 x 10-5
291 Gene Expression Regulation, Enzymologic 7.5 x 10-5
292 AMP-Activated Protein Kinases 7.6 x 10-5
293 Caenorhabditis 7.8 x 10-5
294 Subcellular Fractions 8.1 x 10-5
295 Rhabditoidea 8.3 x 10-5
296 CD4-Positive T-Lymphocytes 8.3 x 10-5
297 Antigens, CD 8.8 x 10-5
298 Portal System 0.00010
299 Ubiquitin-Protein Ligase Complexes 0.00010
300 Tyrosine 3-Monooxygenase 0.00010
301 HIV 0.00010
302 Chromosomes, Human, 6-12 and X 0.00011
303 Amidohydrolases 0.00012
304 Nucleic Acid Hybridization 0.00012
305 Lentiviruses, Primate 0.00012
306 Caspase 3 0.00012
307 Rhabditida 0.00012
308 Antigens, Differentiation 0.00012
309 Caspases, Effector 0.00013
310 Hematopoietic Stem Cells 0.00013
311 Cytoskeletal Proteins 0.00014
312 Chemokines 0.00014
313 Pentosyltransferases 0.00015
314 Cell Division 0.00015
315 Aging 0.00016
316 Lentivirus 0.00016
317 Models, Theoretical 0.00016
318 Cytoprotection 0.00017
319 Core Binding Factor alpha Subunits 0.00017
320 HT29 Cells 0.00018
321 Enhancer Elements, Genetic 0.00018
322 Proto-Oncogene Proteins c-mdm2 0.00018
323 Core Binding Factors 0.00019
324 TGF-beta Superfamily Proteins 0.00020
325 Retroviridae Proteins 0.00020
326 Caspase 8 0.00021
327 Endothelium, Vascular 0.00021
328 Sirtuin 3 0.00021
329 Immunologic Tests 0.00022
330 Genital Diseases, Male 0.00023
331 Protein Interaction Mapping 0.00024
332 Caspase 9 0.00025
333 Benzopyrans 0.00027
334 Cyclins 0.00027
335 Fusion Proteins, bcr-abl 0.00030
336 Genetic Code 0.00032
337 Chromosomes, Human 0.00035
338 Piperazines 0.00036
339 Neuroectodermal Tumors 0.00037
340 Chromosomes, Mammalian 0.00037
341 Pyrans 0.00038
342 Chemical Precipitation 0.00039
343 Chemokines, CXC 0.00040
344 Receptors, Cytokine 0.00045
345 Proto-Oncogene Proteins c-abl 0.00045
346 Urogenital Neoplasms 0.00047
347 Phosphoproteins 0.00048
348 K562 Cells 0.00053
349 Chromosomes 0.00054
350 Genetic Predisposition to Disease 0.00054
351 Chemistry Techniques, Analytical 0.00055
352 Interphase 0.00055
353 Guanine Nucleotide Exchange Factors 0.00059
354 Epithelium 0.00063
355 Endothelium 0.00064
356 NIH 3T3 Cells 0.00064
357 Cercopithecus aethiops 0.00064
358 Insulin-Like Growth Factor I 0.00066
359 Hela Cells 0.00067
360 Response Elements 0.00067
361 Neoplasms, Nerve Tissue 0.00068
362 Cercopithecus 0.00069
363 Citrobacter rodentium 0.00081
364 Caenorhabditis elegans Proteins 0.00082
365 Culture Media, Serum-Free 0.00086
366 Skin Diseases 0.00088
367 Sequence Analysis, DNA 0.00090
368 Adenoviridae 0.00094
369 Proto-Oncogene Proteins c-myc 0.00094
370 Nucleotides 0.00097
371 Androstadienes 0.0010
372 Gene Library 0.0010
373 Mutagenesis 0.0010
374 Caspases, Initiator 0.0011
375 Tumor Suppressor Protein p53 0.0011
376 Neoplasms, Germ Cell and Embryonal 0.0011
377 Neoplasms by Histologic Type 0.0012
378 Somatomedins 0.0012
379 Oncogene Proteins, Fusion 0.0013
380 Cysteine-Rich Protein 61 0.0014
381 Mutant Chimeric Proteins 0.0014
382 Tunica Intima 0.0014
383 Receptor Protein-Tyrosine Kinases 0.0014
384 Glycosyltransferases 0.0014
385 Antigens, Surface 0.0014
386 Glycoproteins 0.0015
387 Collagen Type XI 0.0015
388 Retroviridae 0.0015
389 Myeloproliferative Disorders 0.0015
390 Ovarian Diseases 0.0015
391 Hemic and Immune Systems 0.0016
392 Papilloma, Intraductal 0.0016
393 Transforming Growth Factor beta 0.0016
394 Disease Susceptibility 0.0016
395 Core Binding Factor Alpha 3 Subunit 0.0016
396 Helminth Proteins 0.0017
397 Glypicans 0.0017
398 Threonine 0.0017
399 Tumor Necrosis Factor-alpha 0.0017
400 Tissues 0.0017
401 Linkage Disequilibrium 0.0018
402 Fetus 0.0019
403 Proto-Oncogene Proteins c-pim-1 0.0019
404 Pigment Epithelium of Eye 0.0021
405 Atherosclerosis 0.0021
406 Oxides 0.0021
407 Tumor Markers, Biological 0.0021
408 Oxidants 0.0022
409 Immunologic Memory 0.0022
410 Bone Marrow Cells 0.0023
411 GTP-Binding Protein Regulators 0.0024
412 Mutant Proteins 0.0024
413 Transforming Growth Factors 0.0025
414 Luteinization 0.0025
415 Hematopoietic System 0.0025
416 Hydroxymethylglutaryl-CoA Synthase 0.0026
417 Cell Aging 0.0026
418 Secernentea 0.0026
419 Protein Engineering 0.0027
420 Adnexal Diseases 0.0027
421 Protein-Arginine N-Methyltransferases 0.0029
422 Rhabdomyosarcoma, Alveolar 0.0029
423 Immunohistochemistry 0.0031
424 Ligases 0.0031
425 Antigens 0.0032
426 Cyclin D2 0.0032
427 Acetyl-CoA C-Acetyltransferase 0.0033
428 Antineoplastic Agents 0.0033
429 Interleukin-8 0.0033
430 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 0.0034
431 Transduction, Genetic 0.0035
432 Etoposide 0.0035
433 Ribosomal Protein S6 Kinases, 90-kDa 0.0036
434 Nonheme Iron Proteins 0.0036
435 Genome, Human 0.0037
436 Muscle, Smooth, Vascular 0.0038
437 RNA Interference 0.0038
438 Linkage (Genetics) 0.0040
439 Microphthalmia-Associated Transcription Factor 0.0040
440 Mutagenesis, Site-Directed 0.0041
441 Myostatin 0.0041
442 Podophyllotoxin 0.0042
443 Proto-Oncogene Proteins c-rel 0.0042
444 Hepatocytes 0.0042
445 Receptors, Immunologic 0.0043
446 Proteomics 0.0044
447 Information Science 0.0046
448 Neoplasms, Glandular and Epithelial 0.0047
449 T-Lymphocytes 0.0047
450 Monokines 0.0048
451 Nematoda 0.0048
452 Tamoxifen 0.0050
453 Retinoblastoma-Like Protein p130 0.0050
454 Colony-Stimulating Factors 0.0051
455 Radiation Hybrid Mapping 0.0052
456 Molecular Mechanisms of Pharmacological Action 0.0052
457 Fluorescent Antibody Technique 0.0054
458 Oncogene Protein v-akt 0.0055
459 HIV-Associated Lipodystrophy Syndrome 0.0055
460 Drug Resistance, Neoplasm 0.0057
461 Amyloid beta-Protein 0.0058
462 Extracellular Signal-Regulated MAP Kinases 0.0059
463 Hematopoietic Cell Growth Factors 0.0060
464 Pyruvaldehyde 0.0060
465 National Institutes of Health (U.S.) 0.0060
466 Matrix Metalloproteinases, Secreted 0.0061
467 Skin and Connective Tissue Diseases 0.0061
468 Tretinoin 0.0062
469 fms-Like Tyrosine Kinase 3 0.0062
470 Anions 0.0063
471 Aminoimidazole Carboxamide 0.0063
472 Receptors, TNF-Related Apoptosis-Inducing Ligand 0.0064
473 DNA Damage 0.0065
474 NF-kappa B p50 Subunit 0.0066
475 Myeloid-Lymphoid Leukemia Protein 0.0068
476 Genes, Dominant 0.0068
477 Adenomatous Polyposis Coli Protein 0.0069
478 Basic Helix-Loop-Helix Transcription Factors 0.0070
479 Erythropoietin 0.0071
480 Receptor, Fibroblast Growth Factor, Type 1 0.0071
481 Mitochondria 0.0071
482 Gene Knockdown Techniques 0.0072
483 SKP Cullin F-Box Protein Ligases 0.0073
484 Insulin Antagonists 0.0074
485 cdc25 Phosphatases 0.0074
486 Matrix Metalloproteinase 13 0.0075
487 GTP-Binding Proteins 0.0075
488 Slovenia 0.0076
489 Mixed Function Oxygenases 0.0077
490 Complement Factor H 0.0077
491 Penetrance 0.0078
492 Genetic Association Studies 0.0079
493 Genome-Wide Association Study 0.0079
494 nef Gene Products, Human Immunodeficiency Virus 0.0079
495 Ecdysterone 0.0081
496 Fibroadenoma 0.0084
497 Tetrahydronaphthalenes 0.0086
498 Chromosome Mapping 0.0086
499 GTP Phosphohydrolases 0.0087
500 Spheroids, Cellular 0.0087
501 Androgens 0.0088
502 Protein Tyrosine Phosphatase, Non-Receptor Type 1 0.0088
503 Leukocytes, Mononuclear 0.0088
504 Ubiquitination 0.0090
505 Phosphoric Monoester Hydrolases 0.0090
506 5' Flanking Region 0.0092
507 Bone Marrow Diseases 0.0092
508 Microtubule-Associated Proteins 0.0092
509 Gene Products, nef 0.0093
510 G0 Phase 0.0094
511 CCN Intercellular Signaling Proteins 0.0095
512 Core Binding Factor Alpha 2 Subunit 0.0096
513 Complement C3b Inactivator Proteins 0.0096
514 Ecdysone 0.0097
515 Matrix Metalloproteinases 0.0099
516 Antigens, Nuclear 0.0099
517 Ubiquitin Thiolesterase 0.010
518 Chromosomes, Human, Pair 20 0.010
519 Growth Differentiation Factors 0.010
520 Artificial Gene Fusion 0.010
521 Citrobacter 0.010
522 Receptors, Tumor Necrosis Factor, Type II 0.010
523 Translocation, Genetic 0.010
524 Sequence Alignment 0.011
525 Oxygenases 0.011
526 Receptors, Cell Surface 0.011
527 Pharmacologic Actions 0.011
528 Vertebrate Viruses 0.011
529 Gonadal Disorders 0.011
530 Cyclin E 0.011
531 Amino Acids 0.012
532 Genetic Engineering 0.012
533 Amino Acid Substitution 0.012
534 Glucosides 0.012
535 Peroxidases 0.012
536 Histocytochemistry 0.012
537 Aorta, Thoracic 0.012
538 Haplotypes 0.012
539 Glyoxal 0.012
540 Blood Vessels 0.013
541 Leukocytes 0.013
542 Hyperplasia 0.014
543 Mice, Inbred C57BL 0.014
544 Erythroid Cells 0.014
545 Ions 0.014
546 Dual-Specificity Phosphatases 0.014
547 Glutathione Disulfide 0.014
548 Dendritic Cells 0.014
549 Dermis 0.014
550 Milk Proteins 0.014
551 Breast 0.014
552 Blood Proteins 0.015
553 Amyloid 0.015
554 Lymphocytes 0.015
555 tat Gene Products, Human Immunodeficiency Virus 0.015
556 Iron-Binding Proteins 0.015
557 Monomeric GTP-Binding Proteins 0.015
558 rho-Associated Kinases 0.015
559 Insulin 0.015
560 Chemokine CXCL12 0.016
561 Phosphoserine 0.016
562 Gene Deletion 0.016
563 Proinsulin 0.016
564 Inflammation Mediators 0.017
565 Flow Cytometry 0.017
566 Matrix Metalloproteinase 3 0.017
567 Lithium Chloride 0.017
568 Receptors, Tumor Necrosis Factor, Type I 0.017
569 Disease Progression 0.017
570 Electrolytes 0.017
571 Genomics 0.018
572 Cytophotometry 0.018
573 Thiolester Hydrolases 0.018
574 Pseudogenes 0.018
575 Enzyme Induction 0.019
576 Ecdysteroids 0.019
577 Trabecular Meshwork 0.019
578 Ribosomal Protein S6 Kinases 0.019
579 Peptide Fragments 0.019
580 Multiprotein Complexes 0.019
581 Biotinylation 0.020
582 Neutrophil Activation 0.020
583 Timolol 0.020
584 Estrogen Receptor beta 0.020
585 Annexin A5 0.020
586 Feedback, Physiological 0.020
587 Insulin-Like Growth Factor Binding Protein 3 0.021
588 Comet Assay 0.021
589 Tissue Inhibitor of Metalloproteinase-1 0.021
590 Helminths 0.021
591 Aorta 0.021
592 Chromosomes, Human, Pair 13 0.021
593 Thioredoxins 0.021
594 Pathologic Processes 0.021
595 Gene Products, tat 0.022
596 Exons 0.022
597 Exocrine Glands 0.022
598 Microtubule Proteins 0.022
599 Insulin Resistance 0.022
600 Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 0.022
601 Esterases 0.022
602 Gastrointestinal Neoplasms 0.022
603 Mice, Nude 0.022
604 Lipodystrophy 0.022
605 Vitamin A 0.023
606 Stem Cell Factor 0.023
607 Animal Population Groups 0.023
608 Glycosylation End Products, Advanced 0.023
609 Receptor, IGF Type 1 0.023
610 Cercopithecinae 0.023
611 Carotid Artery Injuries 0.024
612 Cercopithecidae 0.024
613 Tandem Repeat Sequences 0.024
614 Heparan Sulfate Proteoglycans 0.024
615 Cholestenones 0.024
616 Antigen-Presenting Cells 0.024
617 DNA Repair 0.025
618 Viral Envelope Proteins 0.025
619 Protein Tyrosine Phosphatases, Non-Receptor 0.025
620 Stilbenes 0.026
621 Cytosol 0.026
622 Basic-Leucine Zipper Transcription Factors 0.026
623 Paraffin Embedding 0.026
624 Mucin-1 0.026
625 Protein Methyltransferases 0.026
626 G2 Phase 0.026
627 Neoplasms, Fibroepithelial 0.026
628 Amino Acids, Essential 0.026
629 Mononuclear Phagocyte System 0.026
630 bcl-X Protein 0.026
631 omega-N-Methylarginine 0.027
632 Cerebrovascular Trauma 0.027
633 Myosin Heavy Chains 0.027
634 Muscle Cells 0.027
635 Palmitic Acid 0.027
636 Inheritance Patterns 0.028
637 Genetic Markers 0.028
638 Nitric Oxide Synthase 0.028
639 Thapsigargin 0.028
640 Viruses 0.028
641 Protein Isoforms 0.028
642 Hyperinsulinism 0.028
643 Pancreatic Hormones 0.028
644 Sesquiterpenes, Guaiane 0.029
645 Metalloproteins 0.029
646 Immune System 0.029
647 Smad Proteins 0.029
648 Muscle, Smooth 0.029
649 Chromosomes, Human, Pair 8 0.029
650 Vitamin B Complex 0.029
651 Blood 0.030
652 Dexamethasone 0.030
653 Neoplasm Invasiveness 0.031
654 Veins 0.031
655 Viral Matrix Proteins 0.031
656 Neoplasms, Hormone-Dependent 0.031
657 Receptors, Fibroblast Growth Factor 0.031
658 Neoplasm, Residual 0.032
659 Myocytes, Smooth Muscle 0.032
660 Physical Chromosome Mapping 0.033
661 DNA, Intergenic 0.033
662 Retinoids 0.033
663 MicroRNAs 0.033
664 Chromosomes, Human, 19-20 0.033
665 Gene Expression Regulation, Developmental 0.033
666 Leukemia 0.033
667 Hormones 0.034
668 Megakaryocyte-Erythroid Progenitor Cells 0.034
669 Staurosporine 0.035
670 Tissue Embedding 0.036
671 Case-Control Studies 0.036
672 Carotid Arteries 0.036
673 Gene Frequency 0.036
674 Lod Score 0.037
675 Cycloheptanes 0.037
676 Laboratory Techniques and Procedures 0.037
677 Intracellular Fluid 0.037
678 Hormones, Hormone Substitutes, and Hormone Antagonists 0.037
679 Fas Ligand Protein 0.038
680 Mesangial Cells 0.038
681 Neoadjuvant Therapy 0.038
682 Blotting, Northern 0.039
683 Annexins 0.039
684 Hand Strength 0.039
685 Interleukin-3 0.040
686 Electrophoretic Mobility Shift Assay 0.040
687 Sexually Transmitted Diseases, Viral 0.040
688 Cysteine Proteinase Inhibitors 0.040
689 Expressed Sequence Tags 0.041
690 Heterocyclic Compounds, 1-Ring 0.041
691 Drug Resistance 0.041
692 Culture Media 0.041
693 Brain-Derived Neurotrophic Factor 0.041
694 Models, Genetic 0.041
695 Benzylidene Compounds 0.041
696 HIV Infections 0.042
697 Receptors, Somatomedin 0.042
698 Complement Inactivator Proteins 0.042
699 Granulosa Cells 0.042
700 Colon 0.042
701 Amino Acid Oxidoreductases 0.042
702 Wnt Proteins 0.042
703 Molecular Epidemiology 0.042
704 N-Formylmethionine Leucyl-Phenylalanine 0.043
705 Cyclin D 0.043
706 Lithium Compounds 0.043
707 G1 Phase 0.043
708 Biology 0.043
709 Estrogens 0.043
710 Hematologic Neoplasms 0.043
711 Transcription Factor AP-1 0.043
712 Amyloid beta-Protein Precursor 0.043
713 Cardiovascular System 0.044
714 Histological Techniques 0.044
715 N-Formylmethionine 0.044
716 Chromosomes, Human, Pair 11 0.044
717 Lentivirus Infections 0.044
718 Pyrimidines 0.045
719 Anticarcinogenic Agents 0.045
720 Niacinamide 0.045
721 Metalloendopeptidases 0.045
722 Microscopy, Fluorescence 0.045
723 Microglia 0.046
724 Protein Synthesis Inhibitors 0.046
725 Chemotactic Factors, Eosinophil 0.046
726 Tissue Inhibitor of Metalloproteinases 0.046
727 Nitric Oxide Synthase Type III 0.047
728 Balloon Dilatation 0.047
729 Pakistan 0.048
730 Terpenes 0.049
731 Mass Spectrometry 0.049
732 Cyclin-Dependent Kinase Inhibitor p21 0.049
 1-Phosphatidylinositol 3-Kinase   14-3-3 Proteins   5' Flanking Region   Acetyl-CoA C-Acetyltransferase   Acetylation   Active Transport, Cell Nucleus   Adenomatous Polyposis Coli Protein   Adenoviridae   Amino Acid Sequence   Amino Acid Substitution   Aminoimidazole Carboxamide   AMP-Activated Protein Kinases   Amyloid beta-Protein Precursor   Androgens   Androstadienes   Annexin A5   Anoikis   Anticarcinogenic Agents   Antigens, CD95   Aorta, Thoracic   Artificial Gene Fusion   Atherosclerosis   bcl-X Protein   beta Catenin   Biotinylation   Blotting, Northern   Blotting, Western   Brain-Derived Neurotrophic Factor   Caenorhabditis elegans   Caenorhabditis elegans Proteins   Carotid Arteries   Carotid Artery Injuries   CASP8 and FADD-Like Apoptosis Regulating Protein   Caspase 3   Caspase 8   Caspase 9   cdc25 Phosphatases   Cell Aging   Cell Survival   Cell Transformation, Neoplastic   Cercopithecus aethiops   Chemokine CXCL12   Chromatin Immunoprecipitation   Chromosomes, Human, Pair 11   Chromosomes, Human, Pair 13   Chromosomes, Human, Pair 20   Chromosomes, Human, Pair 6   Chromosomes, Human, Pair 8   Citrobacter rodentium   Collagen Type XI   Colon   Comet Assay   Complement Factor H   Core Binding Factor Alpha 2 Subunit   Core Binding Factor Alpha 3 Subunit   COS Cells   Culture Media, Serum-Free   Cyclin D2   Cyclin E   Cyclin-Dependent Kinase Inhibitor p21   Cyclin-Dependent Kinase Inhibitor p27   Cysteine Proteinase Inhibitors   Cysteine-Rich Protein 61   Cytoprotection   Cytosol   Dendritic Cells   Dermis   Dexamethasone   Disease Progression   DNA Primers   DNA Repair   DNA, Complementary   Down-Regulation   Drug Resistance, Neoplasm   Ecdysone   Ecdysterone   Electrophoretic Mobility Shift Assay   Endothelial Cells   Enzyme Activation   Enzyme Induction   Erythropoietin   Estrogen Receptor alpha   Estrogen Receptor beta   Estrogens   Etoposide   Exons   Expressed Sequence Tags   Extracellular Signal-Regulated MAP Kinases   Fas Ligand Protein   Fas-Associated Death Domain Protein   Feedback, Physiological   Fibroadenoma   Flow Cytometry   fms-Like Tyrosine Kinase 3   Forkhead Transcription Factors   Fusion Proteins, bcr-abl   G0 Phase   G1 Phase   G2 Phase   Gene Deletion   Gene Expression Profiling   Gene Expression Regulation, Developmental   Gene Expression Regulation, Neoplastic   Gene Frequency   Gene Knockdown Techniques   Gene Library   Genes, Dominant   Genes, Reporter   Genetic Markers   Genetic Predisposition to Disease   Genome, Human   Genome-Wide Association Study   Glutathione Disulfide   Glycogen Synthase Kinase 3   Glycosylation End Products, Advanced   Glypicans   Granulosa Cells   Guanine Nucleotide Exchange Factors   Hand Strength   Haplotypes   HCT116 Cells   Hela Cells   Hematologic Neoplasms   Hepatocytes   HIV-1   HIV-Associated Lipodystrophy Syndrome   HT29 Cells   Humans   Hydrogen Peroxide   Hydroxymethylglutaryl-CoA Synthase   Hyperplasia   I-kappa B Kinase   Immediate-Early Proteins   Immunologic Memory   Insulin   Insulin Antagonists   Insulin Resistance   Insulin-Like Growth Factor Binding Protein 3   Insulin-Like Growth Factor I   Interleukin-3   Interleukin-8   Jurkat Cells   K562 Cells   Leukemia, Myelogenous, Chronic, BCR-ABL Positive   Linkage Disequilibrium   Lithium Chloride   Lod Score   Longevity   Luciferases   Luteinization   Mammary Glands, Human   Mass Spectrometry   Matrix Metalloproteinase 13   Matrix Metalloproteinase 3   Mesangial Cells   Mice, Inbred C57BL   Mice, Knockout   Mice, Nude   Microarray Analysis   Microglia   Microphthalmia-Associated Transcription Factor   MicroRNAs   Microscopy, Fluorescence   Microtubule-Associated Proteins   Milk Proteins   Mitochondria   Models, Genetic   Mucin-1   Muscle, Smooth, Vascular   Mutagenesis, Site-Directed   Myeloid-Lymphoid Leukemia Protein   Myocytes, Smooth Muscle   Myosin Heavy Chains   Myostatin   N-Formylmethionine Leucyl-Phenylalanine   National Institutes of Health (U.S.)   nef Gene Products, Human Immunodeficiency Virus   Neoadjuvant Therapy   Neoplasm Invasiveness   Neoplasm, Residual   Neoplasms, Hormone-Dependent   Neuroblastoma   Neutrophil Activation   NF-kappa B p50 Subunit   Niacinamide   NIH 3T3 Cells   Nitric Oxide Synthase Type III   omega-N-Methylarginine   Oncogene Protein v-akt   Open Reading Frames   Ovarian Failure, Premature   Oxidants   Oxidative Stress   Pakistan   Palmitic Acid   Papilloma, Intraductal   Paraffin Embedding   Penetrance   Peptide Fragments   Peroxiredoxins   Phosphorylation   Phosphoserine   Pigment Epithelium of Eye   Piperazines   Plasmids   Polymorphism, Single Nucleotide   Prostatic Neoplasms   Protein Binding   Protein Kinase Inhibitors   Protein Synthesis Inhibitors   Protein Tyrosine Phosphatase, Non-Receptor Type 1   Protein-Arginine N-Methyltransferases   Proteomics   Proto-Oncogene Proteins c-akt   Proto-Oncogene Proteins c-mdm2   Proto-Oncogene Proteins c-myc   Proto-Oncogene Proteins c-pim-1   Proto-Oncogene Proteins c-rel   Pseudogenes   PTEN Phosphohydrolase   Pyruvaldehyde   Radiation Hybrid Mapping   Receptor, Fibroblast Growth Factor, Type 1   Receptor, IGF Type 1   Receptors, Androgen   Receptors, Glucocorticoid   Receptors, TNF-Related Apoptosis-Inducing Ligand   Receptors, Tumor Necrosis Factor, Type I   Receptors, Tumor Necrosis Factor, Type II   Recombinant Fusion Proteins   Repressor Proteins   Response Elements   Retinoblastoma-Like Protein p130   Reverse Transcriptase Polymerase Chain Reaction   Rhabdomyosarcoma, Alveolar   rho-Associated Kinases   Ribosomal Protein S6 Kinases, 90-kDa   RNA Interference   RNA, Messenger   RNA, Small Interfering   Sequence Alignment   Shc Signaling Adaptor Proteins   Signal Transduction   Sirtuin 1   Sirtuin 3   SKP Cullin F-Box Protein Ligases   Slovenia   Smad Proteins   Spheroids, Cellular   STAT5 Transcription Factor   Staurosporine   Stem Cell Factor   Superoxide Dismutase   Tamoxifen   tat Gene Products, Human Immunodeficiency Virus   Thapsigargin   Thioredoxins   Threonine   Timolol   Tissue Inhibitor of Metalloproteinase-1   TNF-Related Apoptosis-Inducing Ligand   Trabecular Meshwork   Transcription Factor AP-1   Transcription, Genetic   Transcriptional Activation   Transduction, Genetic   Transfection   Transforming Growth Factor beta   Translocation, Genetic   Tretinoin   Tumor Necrosis Factor-alpha   Tumor Suppressor Protein p53   Tunica Intima   Two-Hybrid System Techniques   Tyrosine 3-Monooxygenase   Ubiquitin Thiolesterase   Ubiquitination   Umbilical Veins   Up-Regulation   Viral Matrix Proteins   Vitamin B Complex   vpr Gene Products, Human Immunodeficiency Virus   Wnt Proteins