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 SOX9
Homo sapiens
 HIF1A
Homo sapiens
 Pax6
Mus musculus
 PAX6
Homo sapiens
 Snai2
Mus musculus
 PPARA
Homo sapiens
 Ppara
Mus musculus
 Thrb
Mus musculus
 SNAI2
Homo sapiens
 Tbr1
Mus musculus
Transcription Factor Encyclopedia  BETA
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Overview
No annotation is available in this section for this article. The content below is taken from a related TF, ZBTB16 (Homo sapiens).

PLZF was expression first identified as a fusion protein with the retinoic acid receptor occurring in acute promyelocytic leukemia (APL). Wild-type PLZF expression appears to be highly regulated across development. In the hematopoietic system, where many functions of PLZF have been reported, levels of PLZF are high in early multipotential progenitor cells, but they decrease as cells become differentiatied and lineage committed. Similarly, PLZF is expressed only in specific populations of T cells. PLZF transcripts were low or absent in conventional CD44high (memory) CD4 and CD8 spleen cells or in Th1 and Th2 cells derived from splenic CD4 cells stimulated with anti-CD3 along with cytokine and anticytokine cocktails. Whereas all CD24low stages of NKT cell development from the CD44low NK1.1− naïve (stage 1) to CD44high NK1.1− effector (stage 2) to the terminally differentiated CD44high NK1.1+ (stage 3) expressed high levels of PLZF. PLZF expression is also high in androgen responsive in human LNCaP cells, but not in other prostate cell lines. There appears to be significant PLZF expression in many normal human tissues of nonhematopoietic origin, including epidermal melanocytes from the foreskin but PLZF expression is decreased in melanoma cell lines.

Expression (automatically populated)
GNF Expression Atlas 2 Data from U133A and GNF1H Chips
Using GNF ID 205883_at that is linked to Ensembl Transcript ID ENST00000392996
1. Fetal brain
-26 
2. Whole brain
37 
 
3. Temporal lobe
23 
4. Parietal lobe
29 
5. Occipital lobe
16 
6. Prefrontal cortex
46 
7. Cingulate cortex
27 
8. Cerebellum
-6 
9. Cerebellum peduncles
-1 
10. Amygdala
-5 
11. Hypothalamus
-22 
12. Thalamus
-29 
13. Subthalamic nucleus
27 
14. Caudate nucleus
-34 
15. Globus pallidus
13 
16. Olfactory bulb
20 
17. Pons
8 
18. Medulla oblongata
23 
 
19. Spinal cord
-24 
20. Ciliary ganglion
0 
21. Trigeminal ganglion
-1 
22. Superior cervical ganglion
0 
23. Dorsal root ganglion
-9 
 
24. Thymus
-6 
25. Tonsil
-33 
26. Lymph node
-24 
27. Bone marrow
-10 
28. BM-CD71+ early erythroid
-65 
29. BM-CD33+ myeloid
-39 
30. BM-CD105+ endothelial
-69 
31. BM-CD34+
11 
32. Whole blood
-32 
 
33. PB-BDCA4+ dentritic cells
-49 
34. PB-CD14+ monocytes
-19 
35. PB-CD56+ NKCells
42 
36. PB-CD4+ Tcells
-1 
37. PB-CD8+ Tcells
18 
38. PB-CD19+ Bcells
-9 
 
39. Leukemia lymphoblastic (molt4)
-48 
40. 721 B lymphoblasts
-50 
41. Lymphoma Burkitts Raji
-13 
42. Leukemia promyelocytic (hl60)
-58 
43. Lymphoma Burkitts Daudi
-28 
44. Leukemia chronic myelogenous (k562)
-68 
45. Colorectal adenocarcinoma
-46 
 
46. Appendix
-1 
47. Skin
5 
48. Adipocyte
51 
49. Fetal thyroid
7 
50. Thyroid
16 
51. Pituitary gland
-17 
 
52. Adrenal gland
14 
53. Adrenal cortex
10 
54. Prostate
44 
55. Salivary gland
-4 
56. Pancreas
2 
57. Pancreatic islets
-5 
 
58. Atrioventricular node
30 
59. Heart
25 
60. Cardiac myocytes
-44 
61. Skeletal muscle
59 
62. Tongue
13 
63. Smooth muscle
-52 
64. Uterus
35 
65. Uterus corpus
-17 
66. Trachea
-10 
 
67. Bronchial epithelial cells
-43 
68. Fetal lung
11 
69. Lung
100 
 
70. Kidney
-20 
71. Fetal liver
-30 
72. Liver
24 
73. Placenta
16 
 
74. Testis
-12 
75. Testis Leydig cell
-12 
76. Testis germ cell
-15 
77. Testis interstitial
-17 
78. Testis seminiferous tubule
4 
79. Ovary
44 
Mouse Brain Expression Data from Allen Brain Atlas